Clinical Research Physician ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
Responsibilities: Recruitment and screening of volunteers and patientsConduct of studiesSupervision of the safety of volunteers/patients during studiesStudy protocols/reportsDevelopment and maintenance of expertise1. Recruitment and screening of volunteers and patients
• Inform volunteers and patients of all aspects of a study, prior to participation, and obtain written and fully informed consent.
• Conduct the clinical evaluation of healthy volunteers and patients for specific studies through thorough medical history and physical examination.
• Inspect laboratory biochemistry, haematology, microbiology, and ECG results and assess their significance in relation to volunteer and patient participation in studies.
• Assess eligibility of subjects for clinical trials against the inclusion and exclusion criteria in the context of sound clinical judgement.
• Assist in maintaining and updating the volunteer database, ensuring a good level of communication with Volunteer Recruitment and Screening Services.
2. Conduct of studies
• Act as Co-Investigator for studies, actively supporting the Principal Investigator in the supervision of the conduct of studies and ensure that the protocol is strictly adhered to, in accordance with ICH-GCP.
• Prescribe study drug in accordance with the protocol.
• Assist in the correct drug dosage and administration procedures as necessary.
• Assist nursing staff in the insertion of intravenous cannulae for venous access utilizing current best practice.
• Assist with collection of blood and other samples as determined by the protocol and Clinical Unit requirements.
• Conduct physician-specific safety and pharmacodynamic assessments as determined by the protocol.
3. Supervision of the safety of volunteers/patients during studies
• Maintain a high standard of subject welfare and safety alongside exemplary data integrity.
• Monitor study subjects at least once daily whilst resident in the Clinical Unit through clinical evaluation, safety laboratory tests, ECG recordings, and other pharmacodynamic assessments as determined by the study protocol, initiating additional procedures where appropriate to enhance subject safety.
• Monitor any adverse reactions should they occur and conduct further examination and investigations based on clinical judgement.
• Complete the Case Report Form with specific reference to the Adverse Event recording, reviewing these frequently and ensuring follow up to resolution.
• Present study-specific safety issues at the weekly Clinical Safety Meetings, ensuring the rest of the physician team are adequately briefed regarding studies for which they have responsibility.
• Ensure good communication with nursing staff with regards to subject welfare and safety.
• Be available on a rostered 24-hour on-call basis for volunteer/patients on a rotational basis.
4. Study protocols/reports
• Assist project management in the leadership of studies.
• Meet and discuss details of studies with representatives of Sponsor companies, helping to develop the protocol, advising on medical and safety issues and providing regular updates to Sponsors as necessary.
• Attend Research Ethics Committee meetings when invited and present proposed study protocols to the Ethics Committee, highlighting specific safety and ethical issues for consideration.
• Take a leading role in the review and development of clinical protocols, summaries, safety, and final study reports.
5. Development and maintenance of expertise
• Develop and maintain a high level of skills in designing, conducting, and interpreting clinical pharmacology studies by reading relevant scientific literature and through attending courses/conferences/symposia.
• Participate in continued professional development (including Higher Medical Training/Specialist Training) through enrolment in courses leading to additional qualifications such as the Diploma in Pharmaceutical Medicine or Diploma in Human Pharmacology.
• Maintain a high level of awareness of major issues in general medicine and the pharmaceutical industry.
• Maintain a high level of clinical skills in the management of medical emergencies, including the management of the cardio-respiratory arrest/peri-arrest scenario in accordance with best medical practice and nationally recognized guidelines, including those published by the Resuscitation Council (UK).
• Maintain acute care skills.
• Take part in regular and systematic audits, responding to the audit results by improving practice, for example by undertaking further training.
• Maintain a training record and portfolio of activity.
• Any other duties as assigned commensurate with skills and qualifications and appropriate to the role.
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Criminal Records Bureau to check for any previous criminal convictions.
What ICON can offer you:
Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work-life balance opportunities for you and your family.
Our benefits examples include:
Various annual leave entitlementsA range of health insurance offerings to suit you and your family's needs.Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.Life assuranceFlexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.ICON, including subsidiaries, is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
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